2017/02/08

Genes are not our fate

DNA is no master controller, nor is it even at the centre of biology

https://www.independentsciencenews.org/health/genetics-is-giving-way-to-a-new-science-of-life/#more-2214

Excerpt: "Test your understanding of the living world with this simple question. What kind of biomolecule is found in all living organisms? If your answer is “DNA”, you are incorrect. The mistake is very forgiveable though. The standard English-language biology education casts DNA (DeoxyriboNucleic Acid) as the master molecule of life, coordinating and controlling most, if not all, living functions. This master molecule concept is popular. It is plausible. It is taught in every university and high school. But it is wrong. DNA is no master controller, nor is it even at the centre of biology. Instead, science overwhelmingly shows that life is self-organised and thus the pieces are in place for biology to undergo the ultimate paradigm shift.


To take a ruthless look at that question is thus the purpose of this article. Does DNA have any claim to being in control? Or at the centre of biological organisation?

The answer is that DNA is none of the things Watson, Lander, and Collins claim, and that even the standard nuanced biologist’s view of life is wrong. This is provable in many ways but mainly by a new science of life that is emerging from almost complete obscurity. This new science explains the features of living beings in productive new ways that DNA-centric, genetic determinist, biology has not, and cannot.

...RNA also has four bases (A, C, G, and U). But cells make more than one hundred comparable chemical modifications to them. The roles of these modifications are essentially a mystery, but presumably they help RNA perform its many cellular tasks.

RNA is also misunderstood. In a typical human cell, less than 1% of it makes proteins. The remaining 99% has a huge variety of structural, regulatory, and enzymatic functions. Most biologists though might as well be slaves to the central dogma in thinking that RNA is just the intermediate between DNA and protein. Only recently has RNA begun emerging from the shadow of DNA as a far more interesting molecule.

“Human biology is actually far more complicated than we imagine. Everybody talks about the genes that they received from their mother and father, for this trait or the other. But in reality, those genes have very little impact on life outcomes. Our biology is way too complicated for that and deals with hundreds of thousands of independent factors. Genes are absolutely not our fate. They can give us useful information about the increased risk of a disease, but in most cases they will not determine the actual cause of the disease, or the actual incidence of somebody getting it. Most biology will come from the complex interaction of all the proteins and cells working with environmental factors, not driven directly by the genetic code”. (Anand et al., 2008)

My comment: Modern scientists understand that the DNA is not the master controller of life. Genes are just libraries for RNA-mediated cellular processes. Genetic alterations are results of cellular mechanisms impacted of RNA-molecules, proteins, epigenetic factors and several other contributors. DNA is not the centre of evolution. This is why we can observe only variation of organisms but not large scale evolution. All of this is in perfect harmony with Biblical creation and Intelligent Design.