2018/01/18

Rapid human genome degradation - Evolution is not happening

About 20,000 new disease-causing genetic mutations in 2017 in the human DNA at population level - Today the total number is 214,158

https://www.ncbi.nlm.nih.gov/pubmed/28349240?dopt=Abstract

Excerpt from abstract: "The Human Gene Mutation Database (HGMD®) constitutes a comprehensive collection of published germline mutations in nuclear genes that underlie, or are closely associated with human inherited disease. At the time of writing (March 2017), the database contained in excess of 203,000 different gene lesions identified in over 8000 genes manually curated from over 2600 journals. With new mutation entries currently accumulating at a rate exceeding 17,000 per annum, HGMD represents de facto the central unified gene/disease-oriented repository of heritable mutations causing human genetic disease used worldwide by researchers, clinicians, diagnostic laboratories and genetic counsellors, and is an essential tool for the annotation of next-generation sequencing data. The public version of HGMD ( http://www.hgmd.org ) is freely available to registered users from academic institutions and non-profit organisations whilst the subscription version (HGMD Professional) is available to academic, clinical and commercial users under license via QIAGEN Inc."
 

My comment: Modern scientists are not aware of random beneficial mutations in the human DNA. Even the famous lactose tolerance is not based on genetic mutations, but different methylation levels of the MCM6 regulatory gene.

http://sciencerefutesevolution.blogspot.fi/2017/02/lactase-persistence-genotype-data-is.html


Rapid genetic degradation is a scientific fact all over nature. It can be observed as gene loss, decreasing number of chromosomes, increasing amounts of heterochromatin in genomes, shortening life spans, susceptibility to diseases, bacteria turning to parasitic or pathogenic bacteria etc. You can easily find information about the Madeira Mouse who lost over half of its chromosomes just in 500 years or the Red Fox who has 1,500 protein coding genes fewer than its descendants. Or the Red Muntjac who has only 3 pairs of chromosomes left. There are no mechanisms resulting in evolution due to rapid genetic degradation. Changes we can observe in organisms are due to epigenetic control of gene expression OR loss of genetic information. Don't be deceived.